Israeli scientists told what foods increase cancer risk
Foods rich in antioxidants such as black tea, chocolate, nuts and berries, can increase the risk of developing certain types of cancer, found a group of researchers from the Centre for immunology and cancer research behalf of Lautenberg at the Hebrew University in Jerusalem, reported the press service of the institution.
"A thorough analysis revealed the culprit that causes cancer to spread rapidly in the large intestine: the intestinal flora that produces metabolites known as "antioxidants", which in high concentrations in foods such as black tea, chocolate, nuts and berries," - said in a press release released by the Hebrew University.
A group of researchers under the guidance of Professor Inon Ben-Neria focused on the role of the intestinal microflora, studying cancer of the gastrointestinal tract, and may have found the reason why only 2% of cancers develop in the small intestine, whereas 98% are striking in the large intestine. The reason, according to scientists, lies in the main difference between these bodies in the presence of the intestinal microflora. In the small intestine the little bacteria, while the colon is inhabited by a rich microflora.
A key role in the development of cancer, according to scientists, plays a protein called p53, which acts as a cellular barrier, inhibiting genetic mutations in the cell. When it is damaged, it not just stops to protect the cell, but rather stimulates the development of cancer by helping the tumor to spread and grow.
To study the effect of intestinal microflora, the researchers introduced a mutated p53 proteins in the thick and the thin intestines. In the small intestine proteins were transformed into normal p53, inhibiting the growth of cancer cells while in the colon they remained true to their nature and provoked the spread of cancer. The culprit, according to Ben-Neria, rich in microorganisms, the environment that exists in the large intestine. To further verify the idea about the role of the microflora of the large intestine, Israeli scientists suppress it with antibiotics, and in this case, the mutated p53 no longer provoke cancer.
When researchers studied how rich in antioxidants diet effect on mice, they found that in this case, their intestinal flora, accelerated mode of stimulation for cancer protein p53.