Disclosed the main mechanisms of aging
Aging cells with the same genetic material and in the same environment can occur in two different ways. The results of the relevant studies published on the portal Phys.org.
Molecular biologists and bioengineers at the University of California in San Diego studied cellular processes in yeast Saccharomyces cerevisiae. Using the methods of microhydrodynamic and computer modeling, scientists have found that about half of the cells get old in the process of gradual reduction of the stability of the nucleolus — region in the nuclear DNA, where the formation of key components for protein synthesis. The other half of the cells dysfunctioning of the mitochondria-the power plants of the cell.
It turned out that one of the two ways of aging is determined at an early age and the cells follow it all his life. However, the researchers using computer simulations have been able to reprogram the main molecular scheme, modifying its DNA and create a new way of aging with increased life expectancy.
Experts intend to continue such studies on other cells and organisms, including human tissues.